文章摘要

下肢动脉硬化闭塞症治疗中载药支架的应用现状

作者: 1卫 任, 1郭 伟
1 中国人民解放军总医院 血管外科,北京 100853
通讯: 郭 伟 Email: guowei@301hospital.com
DOI: 10.3978/.2018.06.002

摘要

近些年下肢动脉硬化闭塞症的腔内治疗技术迅猛发展。基于传统球囊扩张及金属裸支架植入日益凸显的再狭窄问题,各种载药器械相继推出,载药支架即是其中代表之一。载药支架被大量应用于股腘动脉及膝下动脉疾病,相应的临床试验也广泛开展。载药支架在治疗短段病变的安全性、有效性、优越性已得到较为充分的论证,而在长段病变的价值尚需更多临床试验证实。
关键词: 闭塞性动脉硬化;下肢;药物洗脱支架;移植物闭塞,血管

Application status of drug-eluting stent in treatment of lower extremity arterial occlusive disease

Authors: 1WEI Ren, 1GUO Wei
1 Department of Vascular and Endovascular Surgery, Chinese PLA General Hospital, Beijing 100853, China

CorrespondingAuthor:GUO Wei Email: guowei@301hospital.com

Abstract

The techniques of endovascular treatment for arteriosclerotic occlusive disease of lower limbs have developed rapidly in recent years. With the concern of restenosis aft er the traditional balloon dilatation and metal bare stent implantation looming large, various kinds of drug-carrying apparatus have been developed, and the drug eluting stent (DES) is a typical one among them. DES has been widely used in the treatment of femoropopliteal and below-the-knee arterial diseases, and relative clinical trials have also been widely conducted. Th e safety, effi cacy and superiority of DES in treatment of short-segment lesions have been well demonstrated, while its value in treating long-segment lesions still needs to be verifi ed by further clinical trials.
Keywords: Arteriosclerosis Obliterans; Lower Extremity; Drug-Eluting Stents; Graft Occlusion Vascular