甲状腺肿瘤专题研究(Monographic Study of Thyroid Surgery)

预防性颈中央区淋巴结清扫对cN0 分化型甲状腺癌分期与复发危险度分层的意义

Published at: 2015年第24卷第5期

林晓东 1,2 , 陈晓意 1,2 , 黄宝骏 1,2 , 杜嘉林 2 , 赵刚 2 , 彭林 2 , 刘全芳 2 , 黄毅捷 2 , 阴英 2 , 陈政波 2 , 吴泽宇 2
1 汕头大学医学院,广东 汕头 515041
2 广东省人民医院/ 广东省医学科学院 普外二区,广东 广州 510080
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2015.05.003
基金:
广东省科学技术厅科技计划资助项目 2011B031800387

摘要

目的:探讨预防性颈中央区淋巴结清扫在cN0 分化型甲状腺癌(DTC)分期与复发危险度分层中的意义。方法:对2014 年3 月—7 月收治的95 例cN0 DTC 行甲状腺切除及预防性中央区淋巴结清扫患者的临床病理资料行回顾性分析。结果:95 例患者预防性中央区淋巴结清扫术后,43 例见颈中央区淋巴结转移(45.3%),其中10 例(10.5%)肿瘤TNM 分期上移,分别为I 期→ III 期8 例,II 期→ III 期2 例;39 例(41.1%)复发危险度提高。结论:预防性颈中央区淋巴结清扫能提高cN0 DCT 患者TNM 分期和复发危险度分层的准确性,从而有助于术后治疗方案的确定。


Significance of prophylactic central lymph node dissection in tumor stage classification and risk stratification of recurrence for cN0 differentiated thyroid carcinoma

Abstract

Objective: To evaluate the significance of prophylactic central lymph node dissection in determining the tumor stage and risk stratification of recurrence for cN0 differentiated thyroid carcinoma (DTC). Methods: The clinicopathologoic data of 95 patients with cN0 DTC admitted from March to July 2014 undergoing thyroidectomy with prophylactic central lymph node dissection were retrospectively analyzed. Results: Among the 95 patients who underwent prophylactic central lymph node dissection, central cervical lymph node metastases was found in 43 cases (45.3%), and of them, TNM stage was increased in 10 cases (10.5%) (I to III stage in 8 cases, and II to III stage in 2), and risk stratification of recurrence was elevated in 39 cases (41.1%). Conclusion: Prophylactic central lymph node dissection can improve the accuracy of classification of TNM stage and risk stratification of recurrence in patients with cN0 DTC, and thereby be helpful in postoperative treatment planning.


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引用

引用本文: 晓东 林, 晓意 陈, 宝骏 黄, 嘉林 杜, 刚 赵, 林 彭, 全芳 刘, 毅捷 黄, 英 阴, 政波 陈, 泽宇 吴. 预防性颈中央区淋巴结清扫对cN0 分化型甲状腺癌分期与复发危险度分层的意义[J]. 中国普通外科杂志, 2015, 24(5): 633-637.
Cite this article as: LIN Xiaodong, CHEN Xiaoyi, HUANG Baojun, DU Jialin, ZHAO Gang, PENG Lin, LIU Quanfang, HUANG Yijie, YIN Ying, CHEN Zhengbo, WU Zeyu . Significance of prophylactic central lymph node dissection in tumor stage classification and risk stratification of recurrence for cN0 differentiated thyroid carcinoma[J]. Chin J Gen Surg, 2015, 24(5): 633-637.