文献综述(Review)

激素替代治疗甲状腺术后甲状旁腺功能减退的研究进展

Published at: 2015年第24卷第5期

潘明 1 , 张轶西 2 , 丁巍 1 , 牛志昊 1 , 陈闯 1 , 张弘 1
1 吉林大学第二医院甲状腺外科,吉林 长春 130041
2 吉林大学第二医院肝胆胰外科,吉林 长春 130041
通讯作者 弘 张 Email: zhanghong519@hotmail.com
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2015.05.022
基金:
吉林省科学技术厅科技计划资助项目 201105104

摘要

甲状旁腺功能减退(HypoPT)是甲状腺术后最常见的并发症之一。目前临床仍主要依靠钙剂和维生素D 对症治疗,但存在很多问题。甲状旁腺激素(PTH)替代治疗作为一种新型的治疗方法逐渐被关注,且经过多年来的不断探索取得了较快发展。笔者从PTH 替代治疗的药物、给药方式及对机体的影响等方面介绍其研究进展。


Research progress in hormone replacement therapy for hypoparathyroidism after thyroid surgery

Abstract

Hypoparathyroidism (HypoPT) is one of the most common complications after thyroid surgery. It still mainly relies on calcium supplements and activated vitamin D analogues as symptomatic treatment in clinical practice at present, which comes with many problems. Parathyroid hormone replacement therapy (PTH-RT) as a new treatment modality has increasingly been given attention, and has achieved rapid development after continuous efforts for years. The authors present the research progress in PTH-RT from the aspects of drugs for PTH-RT, drug-delivery methods and physical impacts.


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引用

引用本文: 明 潘, 轶西 张, 巍 丁, 志昊 牛, 闯 陈, 弘 张. 激素替代治疗甲状腺术后甲状旁腺功能减退的研究进展[J]. 中国普通外科杂志, 2015, 24(5): 728-732.
Cite this article as: PAN Ming, ZHANG Yixi, DING Wei, NIU Zhihao, CHEN Chuang, ZHANG Hong . Research progress in hormone replacement therapy for hypoparathyroidism after thyroid surgery[J]. Chin J Gen Surg, 2015, 24(5): 728-732.