临床研究(Clinical Research)

两种减压管放置方法对胰十二指肠切除术后胰瘘的影响分析

Published at: 2016年第25卷第3期

何勇 1 , 张辉 1 , 王正峰 1 , 李汛 1 , 孟文勃 1 , 张磊 1 , 朱晓亮 1 , 田明 1 , 李力宏 1 , 周文策 1
1 兰州大学第一临床学院/ 兰州大学第一医院 普外二科,甘肃 兰州 730000
通讯作者 文策 周 Email: zhouwc129@163.com
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2016.03.017
基金:
中国科学院“西部之光”人才培养计划资助项目 2011-180
中央高校基本科研业务费专项资金资助项目 lzujbky-2012-163/167
甘肃省自然科学研究基金资助项目 1208RJZA219

摘要

目的:探讨胰十二指肠切除术(PD)后减压管的两种放置方法对术后胰瘘发生的影响。方法:回顾性分析2012 年1 月—2014 年10 月期间收治的125 例行胰十二指肠切除术患者的临床资料。其中68 例于主胰管放置引流管减压(胰管组),57 例于胰肠吻合口盲端远端置引流管减压(盲襻组),比较两组术后胰瘘发生率及其他临床指标。结果:全组共发生胰瘘9 例(7.2%),其中盲襻组1 例(1.8%),胰管组8 例(11.8%),所有患者均经过保守治疗治愈出院,盲襻组胰瘘发生率明显低于胰管组(P<0.05),其他并发症发生率两组间差异均无统计学意义(均P>0.05);盲襻组住院时间(20.38 d vs. 27.46 d)及住院费用(5.642 万元vs.6.602 万元)均少于胰管组(均P<0.05);两组患者术后1 年肿瘤复发率、生存率差异无统计学意义(均P>0.05)。结论:PD 术中盲攀减压管的放置能有效降低术后胰瘘的发生。


Effects of two different decompression tube placement methods on pancreatic fistula after pancreaticoduodenectomy

Abstract

Objective: To investigate the effects of two different decompression tube placement methods on pancreatic fistula after pancreaticoduodenectomy (PD). Methods: The clinical data of 125 patients undergoing PD from January 2012 to October 2014 were retrospectively analyzed. Of the patients, 68 cases underwent decompression by insertion of a drainage tube into the main pancreatic duct (pancreatic duct group), and 57 cases underwent decompression by insertion of a drainage tube into the distal part of the blind end of the pancreatic jejunal anastomosis (blind loop group). The incidence of postoperative pancreatic fistula and other clinical variables between the two groups were compared. Results: Pancreatic fistula occurred in 9 cases (7.2%) in the entire group, with one case (1.8%) in blind loop group and 8 cases (11.8%) in pancreatic group, and all cases were cured by conservative treatment and discharged from hospital. The incidence of pancreatic fistula in blind loop group was significantly lower than that in pancreatic duct group (P<0.05), but there was no statistical difference in incidence of other complications between the two groups (all P>0.05). In blind loop group compared with pancreatic duct group, the length of hospital stay (20.38 d vs. 27.46 d) and hospitalization cost (56 420 yuan vs. 66 020 yuan) were significantly reduced (both P<0.05). No statistical difference was noted in postoperative 1-year tumor recurrence and survival rate between the two groups (both P>0.05). Conclusion: The decompression tube placement via blind loop can effectively reduce the incidence of postoperative fistula after PD.


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引用

引用本文: 勇 何, 辉 张, 正峰 王, 汛 李, 文勃 孟, 磊 张, 晓亮 朱, 明 田, 力宏 李, 文策 周. 两种减压管放置方法对胰十二指肠切除术后胰瘘的影响分析[J]. 中国普通外科杂志, 2016, 25(3): 407-412.
Cite this article as: HE Yong, ZHANG Hui, WANG Zhengfeng, LI Xun, MENG Wenbo, ZHANG Lei, ZHU Xiaoliang, TIAN Ming, LI Lihong, ZHOU Wence . Effects of two different decompression tube placement methods on pancreatic fistula after pancreaticoduodenectomy[J]. Chin J Gen Surg, 2016, 25(3): 407-412.