文献综述(Review)

cN0期甲状腺乳头状癌预防性中央区淋巴结清扫的争议与进展

Published at: 2016年第25卷第5期

乔娜 1 , 白雪巍 1 , 王刚 1 , 孙备 1 , 武林枫 1
1 哈尔滨医科大学附属第一临床医学院 胰胆外科,黑龙江 哈尔滨 150001
通讯作者 林枫 武 Email: wulinfeng1020@126.com
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2016.05.018
基金:
国家自然科学基金资助项目 81470887, 81372613,81370565
黑龙江省自然科学基金项目资助 D201152
黑龙江省新世纪优秀人才培养计划 1253-NCET-017

摘要

甲状腺癌是近年来全世界发病率较高的恶性肿瘤之一,乳头状癌是其最常见的病理类型,治疗方式以手术为主,中央区淋巴结为其前哨淋巴结,故转移首先发生于此。对于存在中央区淋巴结转移的甲状腺乳头状癌患者,行中央区淋巴结清扫已被国内外学者所认可,但对于cN0期肿瘤,是否行预防性中央区淋巴结清扫目前尚存争议。笔者就中央区淋巴结的解剖概念、cN0期甲状腺乳头状癌转移规律、高危因素、对预防性淋巴结清扫的不同观点、并发症的预防及术式的选择等方面进行综述,旨在提高此类疾病的认识,为其治疗方式的完善提供参考。


Controversy and progress on prophylactic central neck dissection in cN0 papillary thyroid carcinoma

Abstract

In recent years, thyroid carcinoma is one of the most common malignant tumors worldwide, with papillary adenocarcinoma as the predominant pathological type and surgery as the main treatment option. Metastases frequently occur first in the central compartment where the sentinel lymph nodes are located. For patients with central compartment lymph node metastasis, central neck dissection has been becoming widely accepted by domestic and international scholars. However, as for cN0 tumor, whether or not prophylactic central neck dissection should be done is controversial. Here, the authors address the issues that include the anatomical features of the central compartment, and metastatic characteristics and high-risk factors as well as different views regarding prophylactic central neck dissection in cN0 papillary thyroid carcinoma, so as to enhance the understanding of this disease and provide reference for improvement in its treatment.


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引用

引用本文: 娜 乔, 雪巍 白, 刚 王, 备 孙, 林枫 武. cN0期甲状腺乳头状癌预防性中央区淋巴结清扫的争议与进展[J]. 中国普通外科杂志, 2016, 25(5): 729-734.
Cite this article as: QIAO Na, BAI Xuewei, WANG Gang, SUN Bei, WU Linfeng . Controversy and progress on prophylactic central neck dissection in cN0 papillary thyroid carcinoma [J]. Chin J Gen Surg, 2016, 25(5): 729-734.