临床研究(Clinical Research)

肝细胞腺瘤的诊断与治疗:附1例报告并文献复习

Published at: 2017年第26卷第1期

洪育蒲 1 , 熊星铖 1 , 郭闻一 1 , 余佳 1 , 赵亮 1 , 王卫星 1
1 武汉大学人民医院 普通外科,湖北 武汉 430060
通讯作者 卫星 王 Email: sate.llite@163.com
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2017.01.014
基金:
国家自然科学基金资助项目 81370562
国家自然科学基金青年科学基金资助项目 81300356

摘要

目的:探讨肝细胞腺瘤(HCA)的临床特点、影像学表现及其鉴别诊断,以期对其进行准确诊断和治疗。方法:回顾性分析收治的1例HCA患者资料,并复习相关文献。结果:术前影像学检查提示肝右叶占位性病变,肿瘤标志物均阴性,血清γ-谷氨酰转移酶升高。行肝脏V及部分VIII段切除,病理诊断为肝右叶HCA。术后随访2个月,患者恢复良好,复查实验室指标、腹部CT未见异常。结论:HCA为一种少见的肝脏良性肿瘤,常无明显临床症状,术前CT和MRI增强扫描能提高该病诊断率。考虑到HCA有出血倾向及癌变可能,手术切除是其主要的治疗方式,且预后良好。


Diagnosis and treatment of hepatocellular adenoma: a report of one case and literature review

Abstract

Objective: To investigate the clinical features, imaging manifestations and differential diagnosis of hepatocellular adenoma (HCA), for its accurate diagnosis and effective treatment. Methods: The clinical data of one HCA patient admitted recently was analyzed retrospectively, and the relevant literature was reviewed. Results: The preoperative imaging examinations of the patient showed a space-occupying lesion in the right lobe of the liver, and all tumor markers were negative but the serum γ-glutamyltransferase level was increased. The patient underwent segment V and partial segment VIII liver resection, and was pathologically diagnosed as HCA of the right hepatic lobe. Postoperative follow-up was conducted for two months, the patient had an uneventful recovery and no abnormality was noted in laboratory parameters or abdominal CT scan during follow-up visits. Conclusion: HCA is a rare benign liver tumor lacking specific clinical signs. Preoperative CT and contrast-enhanced MRI may improve the diagnostic rates of this disease. Surgical resection is the main treatment method for HCA in consideration of its hemorrhagic tendency and the possibility of malignant transformation, and offers favorable results.


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引用

引用本文: 育蒲 洪, 星铖 熊, 闻一 郭, 佳 余, 亮 赵, 卫星 王. 肝细胞腺瘤的诊断与治疗:附1例报告并文献复习 [J]. 中国普通外科杂志, 2017, 26(1): 83-89.
Cite this article as: HONG Yupu, XIONG Xingcheng, GUO Wenyi, YU Jia, ZHAO Liang, WANG Weixing . Diagnosis and treatment of hepatocellular adenoma: a report of one case and literature review [J]. Chin J Gen Surg, 2017, 26(1): 83-89.