文献综述(Review)

Notch 信号通路在胆管癌中的研究进展

Published at: 2015年第24卷第8期

苏进 1 , 邓小峰 1 , 刘波 1 , 熊力 1 , 文宇 1 , 苗雄鹰 1
1 中南大学湘雅二医院 肝胆外科,湖南 长沙 410011
通讯作者 宇 文 Email: 13787782059@163.com
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2015.08.024
基金:
国家自然科学基金资助项目 81372628

摘要

Notch 通路在肿瘤发生发展、迁移、转移及血管形成方面起着重要作用,也能维持肿瘤干细胞状态,决定其肿瘤形成及分化。笔者就Notch 信号通路在胆管癌中的最新研究进行综述。


Notch signaling pathway in cholangiocarcinoma: recent progress

Abstract

The Notch pathway plays an important role in cancer occurrence, development, migration and metastasis as well as angiogenesis, and is also responsible for the maintenance of the properties of tumor stem cells, and regulating their tumorigenesis and differentiation. In this paper, the authors present the latest progress concerning Notch signaling pathway in cholangiocarcinoma.


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引用

引用本文: 进 苏, 小峰 邓, 波 刘, 力 熊, 宇 文, 雄鹰 苗. Notch 信号通路在胆管癌中的研究进展[J]. 中国普通外科杂志, 2015, 24(8): 1175-1180.
Cite this article as: SU Jin, DENG Xiaofeng, LIU Bo, XIONG Li, WEN Yu, MIAO Xiongying . Notch signaling pathway in cholangiocarcinoma: recent progress[J]. Chin J Gen Surg, 2015, 24(8): 1175-1180.