文章摘要

生物碱对急性胰腺炎的治疗作用及机制研究进展

作者: 1黄昊苏, 1彭杰
1 中南大学湘雅医院 消化内科，湖南 长沙 410008
通讯: 彭杰 Email: pengjie2014@csu.edu.cn
DOI: 10.3978/.2018.03.016
基金: 国家自然科学基金资助项目（81670589）；教育部留学回国人员科研启动基金资助项目（49-20140331）；湖南省卫生计生委课题资助项目（B20180730）。

摘要

急性胰腺炎（AP）是一种临床上常见的消化系统疾病，目前已有大量研究表明多类生物碱可以对AP，尤其是对重症急性胰腺炎（SAP）的治疗发挥作用。生物碱在植物界中分布较广，多数存在于双子叶植物中。笔者就目前已知的几类生物碱对AP的治疗作用及其机制研究进展作一综述。
关键词： 急性胰腺炎；生物碱类；综述文献

Research progress of therapeutic effect of alkaloids on acute pancreatitis and their mechanisms

Authors: 1HUANG Haosu, 1PENG Jie
1 Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, China

CorrespondingAuthor:PENG Jie Email: pengjie2014@csu.edu.cn

Abstract

Acute pancreatitis (AP) is a common digestive disease in clinical practice. A large number of studies have showed that many types of alkaloids exert therapeutic effect on AP, especially on severe acute pancreatitis (SAP). Alkaloids are widely distributed in the plant kingdom, and most of them exist in dicotyledonous plants. Here, the authors address the progress concerning the therapeutic effect of several types of currently known alkaloids on AP and their action mechanisms.
Keywords： Pancreatitis; Alkaloids; Review