文章摘要

EMILIN 蛋白家族与肿瘤的研究进展

作者: 1林峰, 1陶一明, 1王志明
1 中南大学湘雅医院 普通外科，湖南 长沙 410008
通讯: 王志明 Email: wzmxycsu@hotmail.com
DOI: 10.3978/.10.3978/j.issn.1005-6947.2015.11.022
基金: 国家自然科学基金面上基金资助项目, 81372630， 81372631 中南大学湘雅医院2014年度临床 科研基金资助项目, 2014L07

摘要

EMILIN 蛋白家族是一类细胞外基质糖蛋白，参与维持机体组织器官形态与功能的稳态。新近研究表明，EMILIN 可能通过激活某些信号传导通路参与调控肿瘤细胞凋亡和血管新生，在肿瘤生长和侵袭转移过程中发挥关键作用。笔者对其研究进展进行扼要综述。
关键词： 肿瘤 EMILIN 细胞凋亡 新生血管化，病理性 综述文献

EMILIN protein family and tumor: recent advances

Authors: 1LIN Feng, 1TAO Yiming, 1WANG Zhiming
1 Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, China

CorrespondingAuthor:WANG Zhiming Email: wzmxycsu@hotmail.com

Abstract

EMILIN protein family consists of extracellular matrix glycoproteins that participate in maintenance of the structure and function of the organism. Recent studies suggest that EMILIN protein family potentially involves in tumor apoptosis and angiogenesis activating certain signal pathways, and plays a critical role in tumor growth, invasion and metastasis. The authors address the recent research progress in EMILIN protein family.
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