文章摘要

胆管细胞癌的分子病理学研究进展

作者: 1杜渐, 1谭广
1 大连医科大学附属第一医院 肝胆外科，辽宁 大连 116000
通讯: 谭广 Email: tanguangdlyd@163.com
DOI: 10.3978/.10.3978/j.issn.1005-6947.2017.02.018

摘要

胆管细胞癌（CCA）是一类高度异质性的恶性肿瘤，且早期诊断困难，治疗手段及效果有限。因此，更好地明确CCA的分子病理特点对于其诊断、治疗和预后的改善具有重要意义。随着分子生物学技术的发展，CCA分子病理学机制的研究将逐步深入，有望为临床早期诊断和特异性靶向治疗提供新的思路和途径。笔者对CCA分子病理学的最新研究进展进行综述。
关键词： 胆管肿瘤/病因学 病理学，分子 综述文献

Progress in molecular pathological aspects of cholangiocarcinoma

Authors: 1DU Jian, 1TAN Guang
1 Department of Hepatobiliary Surgery, the First Affiliated Hospital, Dalian Medical University, Dalian 116000, China

CorrespondingAuthor:TAN Guang Email: tanguangdlyd@163.com

Abstract

Cholangiocarcinoma (CCA) is a very heterogeneous group of neoplasms, for which the early diagnosis is difficult, present treatment methods are inadequate and the treatment effects are also limited. Thus, a detailed knowledge of the molecular pathological profiles of CCA is important for improving its diagnosis, treatment and outcomes. With the development of molecular biological technologies, the molecular pathological mechanisms of CCA will gradually be revealed and clarified, which may provide new ideas and approaches for early diagnosis and targeted therapy of CCA. Here, the authors present the current research progress in molecular pathology of CCA.
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