文章摘要

主动脉夹层与阻塞性睡眠呼吸暂停低通气综合征关系的临床研究

作者: 1孙占国, 1张学民, 1张小明, 1张韬, 2韩芳, 1蒋京军, 1何长顺
1 北京大学人民医院血管外科，北京 100044
2 北京大学人民医院 呼吸内科，北京 100044
通讯: 张学民 Email: zhangxuemin128@126.com
DOI: 10.3978/.10.3978/j.issn.1005-6947.2015.12.006
基金: 北京大学人民医院研究与发展基金资助项目, RBC2011-20

摘要

目的：研究主动脉夹层与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的关系。 方法：回顾分析41 例合并高血压的主动脉夹层患者的临床资料，设为主动脉夹层组，并选取41 例具 有年龄、性别及体质量指数相近的高血压患者作为对照组，分析OSAHS 与主动脉夹层之间的关系。 结果： 夹层组的阻塞性睡眠呼吸暂停综合征发病率较对照组明显升高（P<0.05）， 且夹层组合并 OSAHS 者睡眠呼吸暂停低通气指数（AHI）较对照组升高，平均SaO2 降低（P<0.05）。 结论：主动脉夹层的发生与睡眠呼吸暂停低通气综合征可能有关。
关键词： 动脉瘤，夹层 睡眠呼吸暂停，阻塞性 高血压 睡眠呼吸暂停低通气指数

The relation between aortic dissection and obstructive sleep apnea and hypopnea syndrome

Authors: 1SUN Zhanguo, 1ZHANG Xuemin, 1ZHANG Xiaoming, 1ZHANG Tao, 2HAN Fang, 1JIANG Jingjun, 1HE Changshun
1 Department of Vascular Surgery, Peking University People’s Hospital, Beijing 100044, China
2 Department of Respiratory Medicine, Peking University People’s Hospital, Beijing 100044, China

CorrespondingAuthor:ZHANG Xuemin Email: zhangxuemin128@126.com

Abstract

Objective: To study the relationship between aortic dissection and obstructive sleep apnea and hypopnea syndrome (OSAHS). Methods: A total of 41 aortic dissection patients with hypertension (study group) and 41 hypertensive patients (control group) of similar age, sex, and body mass index were studied by clinical questionnaire and polysomnography. Results: The prevalence of OSAHS in the aortic dissection group was higher than that in the control group (P<0.05). The aortic dissection patients complicated with OSAHS had a higher AHI and lower average oxygen saturation (P <0.05). Conclusion: Obstructive sleep apnea and hypopnea syndrome may be a risk factor for aortic dissection.
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