文章摘要

Notch 信号通路在胆管癌中的研究进展

作者: 1苏进, 1邓小峰, 1刘波, 1熊力, 1文宇, 1苗雄鹰
1 中南大学湘雅二医院 肝胆外科，湖南 长沙 410011
通讯: 文宇 Email: 13787782059@163.com
苗雄鹰 Email: 4896142@qq.com
DOI: 10.3978/.10.3978/j.issn.1005-6947.2015.08.024
基金: 国家自然科学基金资助项目, 81372628

摘要

Notch 通路在肿瘤发生发展、迁移、转移及血管形成方面起着重要作用，也能维持肿瘤干细胞状态，决定其肿瘤形成及分化。笔者就Notch 信号通路在胆管癌中的最新研究进行综述。
关键词： 胆管肿瘤 受体，Notch 综述文献

Notch signaling pathway in cholangiocarcinoma: recent progress

Authors: 1SU Jin, 1DENG Xiaofeng, 1LIU Bo, 1XIONG Li, 1WEN Yu, 1MIAO Xiongying
1 Department of Hepatobiliary Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, China

CorrespondingAuthor:WEN Yu Email: 13787782059@163.com

Abstract

The Notch pathway plays an important role in cancer occurrence, development, migration and metastasis as well as angiogenesis, and is also responsible for the maintenance of the properties of tumor stem cells, and regulating their tumorigenesis and differentiation. In this paper, the authors present the latest progress concerning Notch signaling pathway in cholangiocarcinoma.
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