文章摘要

ALPPS促进剩余肝脏快速增生机制及相关因素研究进展

作者: 1林为东, 1莫经刚
1 浙江省台州市中心医院 肝胆外科，浙江 台州 318000
通讯: 林为东 Email: linweidonglzy@163.com
DOI: 10.3978/.10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2017.08.016

摘要

联合肝脏离断和门静脉结扎的二步肝切除术（ALPSS）是近年来发展起来的一种新型二步肝切除术。ALPPS最大特点是能够在短期内促进剩余肝脏体积（FLR）快速急剧增生，相比传统二步肝切除术，具有更高二期手术完成率和R0切除率，让因FLR不足而无法行根治性切除的肝癌患者有了治愈的希望。笔者对ALPPS促进FLR快速增生机制及相关因素研究进展进行综述。
关键词： 肝肿瘤 肝切除术 肝再生 综述文献

Mechanisms of ALPPS promoting rapid hypertrophy of future liver remnant and relevant factors: recent advances

Authors: 1LIN Weidong, 1MO Jinggang
1 Department of Hepatobiliary Surgery, Taizhou Central Hospital, Taizhou, Zhejiang 318000, China

CorrespondingAuthor:LIN Weidong Email: linweidonglzy@163.com

Abstract

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a new approach for two-stage hepatectomy procedure developed in recent years. The major advantages of ALPPS are offering rapid hypertrophy of the future liver remnant (FLR), and higher rates of the completion of the second-stage procedure and R0 resection compared to the traditional two-stage hepatectomies, which give hope to patients with liver malignancies considered unresectable due to an insufficient FLR. In this paper, the authors address the research progress on the mechanisms of ALPPS causing rapid FLR hypertrophy and relevant factors.
Keywords： Liver Neoplasms hepatectomy Liver Regeneration Review