文章摘要

炎性反应与主动脉夹层诊断及预后关系的研究进展

作者: 1谭孟杰, 1张磊, 1周建, 1景在平
1 第二军医大学长海医院 血管外科，上海 200433
通讯: 周建 Email: zhoujian1-2@163.com
DOI: 10.3978/.10.3978/j.issn.1005-6947.2015.06.020
基金: 国家自然科学基金资助项目, 81273522；81330034

摘要

主动脉夹层（AD）是严重危及患者生命的心血管系统疾病之一，其病情凶险，发病机制复杂。近年来炎性反应在AD 发生发展中的作用逐渐受到重视，并发现炎性反应与AD 的发病及预后关系密切，笔者就炎性反应参与AD 发生发展的可能机制，炎性标记物与AD 诊断的关系，炎性反应对不同分型AD 预后的影响作一综述，并对面临的问题及未来的展望加以阐述。
关键词： 动脉瘤，夹层 炎症 综述文献

Relations of inflammatory reactions with diagnosis and prognosis of aortic dissection: recent progress

Authors: 1TAN Mengjie, 1ZHANG Lei, 1ZHOU Jian, 1JING Zaiping
1 Department of Vascular Surgery, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

CorrespondingAuthor:ZHOU Jian Email: zhoujian1-2@163.com

Abstract

As one of the life-threatening diseases in cardiovascular system, aortic dissection (AD) is an extremely dangerous condition with a complex pathogenesis. In recent years, the role of inflammatory reactions in the development of aortic dissection has increasingly attracted great attention, and many findings have shown that inflammatory reactions contribute greatly to the pathophysiology and outcomes of AD. In this article, the authors address the possible mechanisms for inflammatory reactions participating in the occurrence and development of AD, the relationship between markers of inflammation and diagnosis of AD, and the influence of inflammatory reactions on prognosis of different types of AD, as well as the current problems and future prospects.
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