激素替代治疗甲状腺术后甲状旁腺功能减退的研究进展
| 作者: |
1潘明,
2张轶西,
1丁巍,
1牛志昊,
1陈闯,
1张弘
1 吉林大学第二医院甲状腺外科，吉林 长春 130041 2 吉林大学第二医院肝胆胰外科，吉林 长春 130041 |
| 通讯: |
张弘
Email: zhanghong519@hotmail.com |
| DOI: | 10.3978/.10.3978/j.issn.1005-6947.2015.05.022 |
| 基金: | 吉林省科学技术厅科技计划资助项目, 201105104 |
摘要
甲状旁腺功能减退（HypoPT）是甲状腺术后最常见的并发症之一。目前临床仍主要依靠钙剂和维生素D 对症治疗，但存在很多问题。甲状旁腺激素（PTH）替代治疗作为一种新型的治疗方法逐渐被关注，且经过多年来的不断探索取得了较快发展。笔者从PTH 替代治疗的药物、给药方式及对机体的影响等方面介绍其研究进展。
关键词：
甲状腺切除术
甲状旁腺功能减退症
激素替代疗法
综述文献
Research progress in hormone replacement therapy for hypoparathyroidism after thyroid surgery
CorrespondingAuthor:ZHANG Hong Email: zhanghong519@hotmail.com
Abstract
Hypoparathyroidism (HypoPT) is one of the most common complications after thyroid surgery. It still mainly relies on calcium supplements and activated vitamin D analogues as symptomatic treatment in clinical practice at present, which comes with many problems. Parathyroid hormone replacement therapy (PTH-RT) as a new treatment modality has increasingly been given attention, and has achieved rapid development after continuous efforts for years. The authors present the research progress in PTH-RT from the aspects of drugs for PTH-RT, drug-delivery methods and physical impacts.
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